When an enemy is just about to attack you, a yellow exclamation mark will appear above their head. Eventually he’ll fall, and you’ll get the Challenger Rune. This thing will save your life (and also make you look badass). Until you’ve got him memorized, just try staying at range and picking away with arrows and traps, being mindful of his damaging leap, which you can roll under.

He’s pretty overwhelming until you realize he’s really only got three moves to worry about. Once there, you’ll face your first true “boss” in the game, The Concierge. Where do you find the Challenger Rune? In the Black Bridge, which is accessible if you go from the Prisoner’s Quarters to the Promenade of the Condemned to the Ramparts and then to the Black Bridge. Platform: PlayStation®4 (physical) Release (Europe): August 23rd 2019. Odds are you’re not going to want to mess with it until you’ve unlocked most of the game’s secrets. That is a good idea if you are still familiarizing yourself with the game and do not die very often or if you are going for the build focused on more frequent risky melee battles. The Challenger Rune unlocks the Daily Run mode in Dead Cells, which is ideal if you’re already an expert and you want to compete on the high score list. There’s one more rune that you’ll probably find without our help, but you may be wondering what it does. For your trouble, you’ll nab the final major rune in the game. The elite holding the Spider Rune is at the bottom of a pit marked with a skull flag, so drop down and do your best to survive. Go slow and keep an eye out for your target. The Slumbering Sanctuary is a beast of a zone and will require constant vigilance. Defeat it, and you’ll be able to head into the Slumbering Sanctuary. The Insufferable Crypt houses a tricky boss fight with a giant eye creature. From the Prisoner’s Quarters, head to the Toxic Sewers (using the Vine Rune) and then into the Ancient Sewers (using the Ram Rune), then from the Ancient Sewers to the Insufferable Crypt. To access this dangerous zone, you’ll need to follow a specific route that leads there. It’s also the hardest to get, requiring that you unlock all of the previous runes. It’s arguably the most helpful of the bunch as it lets you run up, hang and jump off any wall. The innermost layer is the heartwood, made up of dead cells that form a hard, strong core that helps support the tree. The final ability rune in Dead Cells is the Spider Rune.

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